Running head: B12 MALABSORPTION IN erstwhile(a) ADULTS: THE PATHOPHYSIOLOGICAL RESPONSE ! 1 Pathophysiological resolving power to Vitamin B12 Ingestion and the Clinical Implications of Malabsorption in the Senior Population: A Review of Available Literature Running head: B12 MALABSORPTION IN OLDER ADULTS: THE PATHOPHYSIOLOGICAL RESPONSE ! 2 Introduction The active subdivision in colored deemed the anti-pernicious anemia factor, was largely undiagnosed until 1948, when cobalamin (vitamin B12) was detached by two chemists, Karl A. Folkers (1906-1997) and Alexander R. Todd (1907-1997) (Shampo, Kyle, & Steensma, 2006). It has been much than 60 long time since the disc all overy of vitamin B12, and researchers have non accurately documented the dependable prevalence of cobalamin insufficiency in the general population. blood serum B12 concentrations in the US population were reported in the field of study wellness and Nutrition Examination Surveys conducted from 1 999 to 2002 (Pfeiffer et al., 2007). These surveys showed that the prevalence of B12 deficiency (serum levels little than 148 pmol/L) varied by age, group and number of people affected. It was documented that little than 3% of the population old 20 to 39 years, 4% of those aged 40 to 59 years, and around 6% of persons aged 70 years or much were deficient in B12.
The study also demonstrated that marginal B12 deficiency (148-221 pmol/L) occurred more commonly in individuals between the ages of 20 to 59 (14% -16%) and over 60 years (20%) of age. The focus of this report is to brushup the gentlemans gentleman path ophysiological response to vitamin B12 inges! tion, the clinical implications of vitamin B12 malabsorption in the senior population, and to set sullen the clinical manifestations associated with a B12 deficient state. Pathophysiological Response to Vitamin B12 Ingestion Vitamin B12 that is ingested from wolf proteins in food is absorbed and metabolized through a grammatical construction complex system that depends on adequate function of the stomach, intestines and pancreas. The metabolic...If you privation to come up a full essay, order it on our website: BestEssayCheap.com
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